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Home > Products >  Halofuginon Lactate

Halofuginon Lactate CAS NO.82186-71-8

  • Min.Order: 1 Gram
  • Payment Terms: L/C,T/T
  • Product Details

Keywords

  • 82186-71-8
  • Halofuginon Lactate
  • Halofuginon

Quick Details

  • ProName: Halofuginon Lactate
  • CasNo: 82186-71-8
  • Molecular Formula: C19H23BrClN3O6
  • Appearance: Off-white to white solid
  • Application: Halofuginone is a coccidiostat used in...
  • DeliveryTime: With 7 work days after payment confirm...
  • PackAge: Per request
  • Port: Shanghai
  • ProductionCapacity: 1 Metric Ton/Year
  • Purity: 98%
  • Storage: Under room temperature
  • Transportation: By express/air/sea
  • LimitNum: 1 Gram
  • Grade: Other

Superiority

watson international ltd is the only supplier globally who can make halofuginone and its derivatives in mt scale.
 

watson international ltd' has a very strong r&d and technical capacity supported by fcad's platform. the subsidiaries under fcad group have accumulated much know-how of different fine chemical branches. for example, apnoke scientific ltd is the expert in amino acid and peptide, ulcho biochemical ltd focuses on carbohydrate and nucleotide, caming pharmaceutical ltd develops new technology for pharmaceutical chemicals and warshel chemical ltd is the expert of advanced materials and performance chemicals including catalysts, resins, electronic chemicals and agrochemicals.

 

fcad helps clients from different fields to develop their required fine chemicals or formulations. from pharmaceutical materials to diagnostic reagents, cruing agent to construction chemicals, photographic formulations to electronic intermediates, cosmetics ingredients to flavors, fcad and the subsidiaries try to achieve high quality by the most economic route. our clients include ge, p&g, siemens, sony, pfizer, merck, astrazeneca, sigma-aldrich, tci and so on.

 

we are constantly upgrading every aspect of our quality systems in terms of staff training, documentation and analytical capabilities to achieve the highest levels possible. the quality of our products is one of our most significant assets. we constantly seek ways to improve our quality systems and welcome any suggestions from our customers or regulatory groups on how to do this. we have the following procedures in our quality systems to monitor the quality of products throughout the whole manufacturing process and even up to inventory.

 

mature product line ensures of stability of production and many products with different levels of stock or intermediate inventory enable us to meet your needs quickly. watson understands every provided product's shipment and storage conditions and will use professional packages and labels regularly or per customer's request.

 

mature product line with the industrialization of the production process allows us to effectively control costs and offer you the best price. we are also optimizing the current route of our products to make it possible of costing down for future needs. and in order to serve customers such as universities, r&d institutions, labs and non-profit organizations, watson accepts multiple payment methods including wire transfer, paypal, alibaba escrow, western union, moneygram or even bitcoin.

 

 

Details

Identification

CAS Number

82186-71-8

Name

Halofuginon Lactate

Synonyms

2-Hydroxypropanoic acid – 7-bromo-6-chloro-3-{3-[(2S,3R)-3-hydroxy-2-piperidinyl]-2-oxopropyl}-4(3H)-quinazolinone (1:1) [ACD/IUPAC Name]
2-Hydroxypropansäure –7-brom-6-chlor-3-{3-[(2S,3R)-3-hydroxy-2-piperidinyl]-2-oxopropyl}-4(3H)-chinazolinon (1:1) [German] [ACD/IUPAC Name]
Acide 2-hydroxypropanoïque – 7-bromo-6-chloro-3-{3-[(2S,3R)-3-hydroxy-2-pipéridinyl]-2-oxopropyl}-4(3H)-quinazolinone (1:1) [French] [ACD/IUPAC Name]
Propanoic acid, 2-hydroxy-, compd. with 7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone (1:1) [ACD/Index Name]
2-Hydroxypropanoic acid [ACD/IUPAC Name]
7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxy-2-piperidyl]-2-oxo-propyl]quinazolin-4-one
7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxy-2-piperidyl]-2-oxo-propyl]quinazolin-4-one;2-hydroxypropanoic acid
7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one
7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one and 2-hydroxypropanoic acid
82186-71-8 [RN]
Halofuginone lactate
Halofuginone lactate 100 g/mL in Acetonitrile
Halofuginone lactate 100 µg/mL in Acetonitrile – short expiry, for immediate use only

Molecular Structure

Structure of Halofuginon Lactate CAS 82186-71-8

Structure of Halofuginon Lactate CAS 82186-71-8

SMILES

CC(C(=O)O)O.c1c2c(cc(c1Cl)Br)ncn(c2=O)CC(=O)C[C@H]3[C@@H](CCCN3)O

StdInChI

InChI=1S/C16H17BrClN3O3.C3H6O3/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;1-2(4)3(5)6/h5-6,8,14-15,19,23H,1-4,7H2;2,4H,1H3,(H,5,6)/t14-,15+;/m0./s1

StdInChIKey

GATQERNJKZPJNX-LDXVYITESA-N

Molecular Formula

C19H23BrClN3O6

Molecular Weight

504.76

Properties

Appearance

Off-white to white solid

Safety Data

WGK Germany

3

Specifications and Other Information of Our Halofuginon Lactate CAS 82186-71-8

Standard

Enterprise standard

Identification Methods

HPLC/HNMR

Purity

98%min

Package

According to customer requirements to packaging

Storage

Under the room temperature and away from light

Application

Halofuginone is a coccidiostat used in veterinary medicine. It is a synthetic halogenated derivative of febrifugine, a natural quinazolinone alkaloid which can be found in the Chinese herb Dichroa febrifuga (Chang Shan).Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and it has received orphan drug designation from the U.S. Food and Drug Administration.
Halofuginone inhibits the development of T helper 17 cells, immune cells that play an important role in autoimmune disease, but it does not affect other kinds of T cells which are involved in normal immune function.Halofuginone therefore has potential for the treatment of autoimmune disorders.
Halofuginone is also an inhibitor of collagen type I gene expression and as a consequence it may inhibit tumor cell growth.Halofuginone exerts its effects by acting as a high affinity inhibitor of the enzyme Glutamyl-Prolyl tRNA synthetase. Inhibition of prolyl tRNA charging leads to the accumulation of uncharged prolyl tRNAs, which serve as a signal to initiate the amino acid starvation response, which in turn exerts anti-inflammatory and anti-fibrotic effects.

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Friend Links:FCAD Group Official WebsiteWatson Noke Scientific LtdApnoke Scientific LtdUlcho Biochemical LtdCaming Pharmaceutical LtdWarshel Chemical Ltd

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