Cloprostenol isopropyl ester CAS NO.157283-66-4

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Product Details

Keywords

Cloprostenol isopropyl ester
157283-66-4
Cloprostenol isopropyl ester

Quick Details

ProName: Cloprostenol isopropyl ester
CasNo: 157283-66-4
Molecular Formula: C25H35ClO6
Appearance: Colorless to Yellow oil
Application: The intermediate of Cloprostenol. (+)...
DeliveryTime: With 7 work days after payment confirm...
PackAge: Per request
Port: shanghai
ProductionCapacity: 1 Kiloliter/Month
Purity: 97%
Storage: Store at the 2-8℃
Transportation: By Sea, Air, Express
LimitNum: 1 Gram
Grade: Pharma Grade

Superiority

The intermediate of Cloprostenol. (+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF2α in terminating pregnancy when given subcutaneously at a daily dose of 0.125 μg/kg in rats and hamsters, without the side effects associated with PGF2α.1 (+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 x 10-12 M.2 Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol.

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Details

Identification

CAS Number

157283-66-4

Name

Cloprostenol isopropyl ester

Synonyms

(5Z)-7-{(1R,2R,3R,5S)-2-[(3R)-4-(3-Chlorophénoxy)-3-hydroxy-1-butén-1-yl]-3,5-dihydroxycyclopentyl}-5-hepténoate d’isopropyle [French] [ACD/IUPAC Name]
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z)- [ACD/Index Name]
Isopropyl (5Z)-7-{(1R,2R,3R,5S)-2-[(3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-5-heptenoate [ACD/IUPAC Name]
Isopropyl-(5Z)-7-{(1R,2R,3R,5S)-2-[(3R)-4-(3-chlorphenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-5-heptenoat [German] [ACD/IUPAC Name]
(+)-9,11,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester
(+)-Cloprostenol isopropyl ester
157283-66-4 [RN]
ISOPROPYL CLOPROSTENATE

Molecular Structure

Structure of Cloprostenol isopropyl ester CAS 157283-66-4

SMILES

CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1C=C[C@H](COc2cccc(c2)Cl)O)O)O

StdInChI

InChI=1S/C25H35ClO6/c1-17(2)32-25(30)11-6-4-3-5-10-21-22(24(29)15-23(21)28)13-12-19(27)16-31-20-9-7-8-18(26)14-20/h3,5,7-9,12-14,17,19,21-24,27-29H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12/t19-,21-,22-,23+,24-/m1/s1

StdInChIKey

OCNSAYQJDKJOLH-JSMWQALTSA-N

Molecular Formula

C25H35ClO6

Molecular Weight

466.99

Properties

Appearance

Colorless to Yellow oil

Specifications and Other Information of Our Cloprostenol isopropyl ester CAS 157283-66-4

Standard

Enterprise standard

Identification Methods

HPLC

Purity

97% min

Water

1.0% max

Single Impurity

0.5% max

Total Impurities

1.5% max

Storage

2-8°C away from light

Application

The intermediate of Cloprostenol.
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF2α in terminating pregnancy when given subcutaneously at a daily dose of 0.125 μg/kg in rats and hamsters, without the side effects associated with PGF2α.1 (+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 x 10-12 M.2 Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol.