United Kingdom
- Product Details
Keywords
- Travoprost
- 157283-68-6
- Travatan
Quick Details
- ProName: Travoprost
- CasNo: 157283-68-6
- Molecular Formula: C26H35F3O6
- Appearance: Light yellow to almost colourless oil
- Application: Travoprost ophthalmic solution is a to...
- DeliveryTime: With 7 work days after payment confirm...
- PackAge: Per request
- Port: shanghai
- ProductionCapacity: 500 Kilogram/Month
- Purity: 96.0%-102%
- Storage: Glass bottle, 2-8°C for shipment and 0...
- Transportation: By Sea, Air, Express
- LimitNum: 1 Gram
- Grade: Pharma Grade
Superiority
Watson International Ltd' has a very strong R&D and technical capacity supported by FCAD's platform. The subsidiaries under FCAD Group have accumulated much know-how of different fine chemical branches. For example, Apnoke Scientific Ltd is the expert in Amino Acid and Peptide, Ulcho Biochemical Ltd focuses on Carbohydrate and Nucleotide, Caming Pharmaceutical Ltd develops new technology for pharmaceutical chemicals and Warshel Chemical Ltd is the expert of Advanced Materials and Performance Chemicals including Catalysts, Resins, Electronic Chemicals and Agrochemicals.
FCAD helps clients from different fields to develop their required fine chemicals or formulations. From pharmaceutical materials to diagnostic reagents, cruing agent to construction chemicals, photographic formulations to electronic intermediates, cosmetics ingredients to flavors, FCAD and the subsidiaries try to achieve high quality by the most economic route. Our clients include GE, P&G, Siemens, Sony, Pfizer, Merck, AstraZeneca, Sigma-Aldrich, TCI and so on.
We are constantly upgrading every aspect of our quality systems in terms of staff training, documentation and analytical capabilities to achieve the highest levels possible. The quality of our products is one of our most significant assets. We constantly seek ways to improve our quality systems and welcome any suggestions from our customers or regulatory groups on how to do this. We have the following procedures in our quality systems to monitor the quality of products throughout the whole manufacturing process and even up to inventory.
Mature product line ensures of stability of production and many products with different levels of stock or intermediate inventory enable us to meet your needs quickly. Watson understands every provided product's shipment and storage conditions and will use professional packages and labels regularly or per customer's request.
Details
Identification
CAS Number
157283-68-6
Name
Travoprost
Synonyms
(+/-)-16-(M-TRIFLUOROMETHYLPHENOXY)TETRANORPROSTAGLANDIN F2
15(S)-FLU-IPR
15(S)-FLUPROSTENOL ISOPROPYL ESTER
(+)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
9ALPHA,11ALPHA,15S-TRIHYDROXY-16(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
(+)-FLUPROSTENOL ISOPROPYL ESTER
FLUPROSTENOL ISOPROPYL ESTER
FLU-IPR
1-methylethyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoate
Travatan
Travatan Z
Molecular Structure
SMILES
FC(F)(F)c2cc(OC[C@H](O)/C=C/[C@@H]1[C@H]([C@@H](O)C[C@H]1O)CC=C/CCCC(=O)OC(C)C)ccc2
StdInChI
InChI=1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21-,22-,23+,24-/m1/s1
StdInChIKey
MKPLKVHSHYCHOC-AHTXBMBWSA-N
Molecular Formula
C26H35F3O6
Molecular Weight
500.5477
Properties
Appearance
Light yellow to almost colourless oil
Flash Point
307.5°C
Boiling Point
584.8°C at 760 mmHg
Density
1.245g/ml
Refractive Index
1.547
Safety Data
Symbol
GHS02, GHS07
Risk Statements (Europe)
Safety Statements (Europe)
16-26-36
Specifications and Other Information of Our Travoprost CAS 157283-68-6
Standard
USP34
Identification Methods
HPLC, TLC
Assay
96.0%-102%
Solubility
Soluble in chloroform,ethyl acetate, acetone, practically insoluble in water
Specific Rotation
+52°～+58°,(C=1 CH2Cl2)
Water
≤1.0%
Related Compounds
Epoxide derivative ≤0.40%
15-epi Diastereomer ≤0.1%
5,6-trans Isomer ≤3.5%
15-Keto derivative ≤0.3%
Any other impurities ≤0.1%
Total other impurity ≤1.0%
Related Solvents
Isopropanol ≤0.5%
Ethyl acetate ≤0.25%
n-Hexane ≤0.029%
Ethanol ≤0.5%
Known Application
Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure.
Package
Plastic bag inside and paper drum outside.
Productivity
kg scale/month
Storage
Glass bottle, 2-8°C for shipment and 0 ℃ for long time storage
General View of Documents
Travoprost-CAS-157283-68-6-NMR1
Travoprost-CAS-157283-68-6-NMR2
Travoprost-CAS-157283-68-6-NMR3
Available Impurities
Impurity 1
Name: Epoxide Derivative
Chemical Name: (5Z)-(9S,11R,15S)-9,11,15-Trihydroxy-13,14-epoxy-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5-prostadienoic acid, isopropyl ester
Appearance: Yellow oil
Identification: HNMR,MS,HPLC
Purity: 98%min(HPLC)
Impurity 2
Name: 15-epi Diastereomer
Chemical Name: (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxy-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester
Appearance: Yellow oil
Identification: HNMR,MS,HPLC
Purity: 98%min(HPLC)
Structure-of-15-epi-Diastereomer
Impurity 3
Name: 5,6-trans Isomer
Chemical Name: (5E,13E)-(9S,11R,15R)-9,11,15-Trihydroxy-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester
Appearance: Yellow oil
Identification: HNMR,MS,HPLC
Purity: 98%min(HPLC)
Structure-of-56-trans-Isomer
Impurity 4
Name: 15-keto derivative
Full Name: (5Z,13E)-(9S,11R)-9,11-Dihydroxy-15-oxo-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester
Appearance: Yellow oil
CAS: 404830-45-1
Identification: HNMR,MS,HPLC
Purity: 98%min(HPLC)
Structure-of-15-keto-Travoprost-CAS-404830-45-1