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Home > Products >  Travoprost

Travoprost CAS NO.157283-68-6

  • Min.Order: 1 Gram
  • Payment Terms: L/C,D/A
  • Product Details

Keywords

  • Travoprost
  • 157283-68-6
  • Travatan

Quick Details

  • ProName: Travoprost
  • CasNo: 157283-68-6
  • Molecular Formula: C26H35F3O6
  • Appearance: Light yellow to almost colourless oil
  • Application: Travoprost ophthalmic solution is a to...
  • DeliveryTime: With 7 work days after payment confirm...
  • PackAge: Per request
  • Port: shanghai
  • ProductionCapacity: 500 Kilogram/Month
  • Purity: 96.0%-102%
  • Storage: Glass bottle, 2-8°C for shipment and 0...
  • Transportation: By Sea, Air, Express
  • LimitNum: 1 Gram
  • Grade: Pharma Grade

Superiority

Watson International Ltd is is the expert of Prostaglandin class and our mature products include Bimatoprost, Travoprost, 15S-Cloprostenol, Latanoprost, (+)-Cloprostenol sodium, Cloprostenol isopropyl ester and Dechloro dihydroxy difluoro ethylcloprostenolamide as well as their impurities.
 

Watson International Ltd' has a very strong R&D and technical capacity supported by FCAD's platform. The subsidiaries under FCAD Group have accumulated much know-how of different fine chemical branches. For example, Apnoke Scientific Ltd is the expert in Amino Acid and Peptide, Ulcho Biochemical Ltd focuses on Carbohydrate and Nucleotide, Caming Pharmaceutical Ltd develops new technology for pharmaceutical chemicals and Warshel Chemical Ltd is the expert of Advanced Materials and Performance Chemicals including Catalysts, Resins, Electronic Chemicals and Agrochemicals.

 

FCAD helps clients from different fields to develop their required fine chemicals or formulations. From pharmaceutical materials to diagnostic reagents, cruing agent to construction chemicals, photographic formulations to electronic intermediates, cosmetics ingredients to flavors, FCAD and the subsidiaries try to achieve high quality by the most economic route. Our clients include GE, P&G, Siemens, Sony, Pfizer, Merck, AstraZeneca, Sigma-Aldrich, TCI and so on.

 

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Mature product line with the industrialization of the production process allows us to effectively control costs and offer you the best price. We are also optimizing the current route of our products to make it possible of costing down for future needs. And in order to serve customers such as universities, R&D institutions, labs and non-profit organizations, Watson accepts multiple payment methods including wire transfer, Paypal, Alibaba ESCROW, , Moneygram or even Bitcoin.

Details

Identification

CAS Number

157283-68-6

Name

Travoprost

Synonyms

(+/-)-16-(M-TRIFLUOROMETHYLPHENOXY)TETRANORPROSTAGLANDIN F2
15(S)-FLU-IPR
15(S)-FLUPROSTENOL ISOPROPYL ESTER
(+)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
9ALPHA,11ALPHA,15S-TRIHYDROXY-16(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
(+)-FLUPROSTENOL ISOPROPYL ESTER
FLUPROSTENOL ISOPROPYL ESTER
FLU-IPR
1-methylethyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoate
Travatan
Travatan Z

Molecular Structure

structure of Travoprost CAS 157283-68-6

SMILES

FC(F)(F)c2cc(OC[C@H](O)/C=C/[C@@H]1[C@H]([C@@H](O)C[C@H]1O)CC=C/CCCC(=O)OC(C)C)ccc2

StdInChI

InChI=1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21-,22-,23+,24-/m1/s1

StdInChIKey

MKPLKVHSHYCHOC-AHTXBMBWSA-N

Molecular Formula

C26H35F3O6

Molecular Weight

500.5477

Properties

Appearance

Light yellow to almost colourless oil

Flash Point

307.5°C

Boiling Point

584.8°C at 760 mmHg

Density

1.245g/ml

Refractive Index

1.547

Safety Data

Symbol

flame-jpgexclamation-mark-jpgGHS02, GHS07

Risk Statements (Europe)

11-36/37/38

Safety Statements (Europe)

16-26-36

Specifications and Other Information of Our Travoprost CAS 157283-68-6

Standard

USP34

Identification Methods

HPLC, TLC

Assay

96.0%-102%

Solubility

Soluble in chloroform,ethyl acetate, acetone, practically insoluble in water

Specific Rotation

+52°~+58°,(C=1 CH2Cl2)

Water

≤1.0%

Related Compounds

Epoxide derivative ≤0.40%
15-epi Diastereomer ≤0.1%
5,6-trans Isomer ≤3.5%
15-Keto derivative ≤0.3%
Any other impurities ≤0.1%
Total other impurity ≤1.0%

Related Solvents

Isopropanol ≤0.5%
Ethyl acetate ≤0.25%
n-Hexane ≤0.029%
Ethanol ≤0.5%

Known Application

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure.

Package

Plastic bag inside and paper drum outside.

Productivity

kg scale/month

Storage

Glass bottle, 2-8°C for shipment and 0 ℃ for long time storage

General View of Documents

Travoprost-CAS-157283-68-6-NMR1

Travoprost-CAS-157283-68-6-NMR1

Travoprost-CAS-157283-68-6-NMR2

Travoprost-CAS-157283-68-6-NMR2

Travoprost-CAS-157283-68-6-NMR3

Travoprost-CAS-157283-68-6-NMR3

Available Impurities

Impurity 1
Name: Epoxide Derivative
Chemical Name: (5Z)-(9S,11R,15S)-9,11,15-Trihydroxy-13,14-epoxy-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5-prostadienoic acid, isopropyl ester
Appearance: Yellow oil
Identification: HNMR,MS,HPLC
Purity: 98%min(HPLC)
Structure-of-1314-Epoxy-derivative-of-Travoprost
Impurity 2
Name: 15-epi Diastereomer
Chemical Name: (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxy-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester
Appearance: Yellow oil
Identification: HNMR,MS,HPLC
Purity: 98%min(HPLC)

Structure-of-15-epi-Diastereomer

Structure-of-15-epi-Diastereomer

Impurity 3
Name: 5,6-trans Isomer
Chemical Name: (5E,13E)-(9S,11R,15R)-9,11,15-Trihydroxy-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester
Appearance: Yellow oil
Identification: HNMR,MS,HPLC
Purity: 98%min(HPLC)

Structure-of-56-trans-Isomer

Structure-of-56-trans-Isomer

Impurity 4
Name: 15-keto derivative
Full Name: (5Z,13E)-(9S,11R)-9,11-Dihydroxy-15-oxo-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester
Appearance: Yellow oil
CAS: 404830-45-1
Identification: HNMR,MS,HPLC
Purity: 98%min(HPLC)

Structure-of-15-keto-Travoprost-CAS-404830-45-1

Structure-of-15-keto-Travoprost-CAS-404830-45-1

 

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